**AI-driven discovery of GPNMB CAR T cells as a multi-cancer therapy** > An AI-

**AI-driven discovery of GPNMB CAR T cells as a multi-cancer therapy**

> An AI-guided framework integrating high-resolution cellular atlases, public knowledge databases, and large language models enables a modular framework for CAR T cell target discovery. GPNMB emerged as a versatile candidate antigen, enabling the development of GPNMB CAR T cells with potent activity in multiple xenograft mouse models of cancer.

**来源信息**
- **来源**：Cell：最新论文（RSS）
- **分类**：tip
- **发布时间**：2026-06-25 08:00（北京时间）
- **原文**：[打开原文](https://www.cell.com/cell/fulltext/S0092-8674(26%2900651-3?rss=yes)